Background: The rise of artificial intelligence (AI) has created growing excitement and much debate about its potential to revolutionize entire industries, particularly with recent developments in generative AI, which can create text, images, audio, video, and other content when prompted by a user. Use of generative AI has exploded. The technology may increase productivity and transform daily tasks in many industries. However, it may also displace workers, help spread false information and create or elevate risks to national security. As federal agencies deploy generative AI to help improve operations and service delivery and develop their generative AI policy by Dec. 2025, the Office of Management and Budget has directed agencies to accelerate the federal use of AI technologies by prioritizing innovation, governance, and public trust. This review is the fourth in a body of work on generative AI and will examine federal use and management of the technology. Key Questions: 1) How are selected agencies using or planning to use generative AI? 2) What challenges are selected agencies facing with current and future use and management of generative AI? 3) How are selected agencies managing the current and future use of generative AI?