Suicide deaths outnumber those caused by traffic accidents or gender violence. So much so that, in 2020, suicide was the leading external cause of mortality in Spain, with 3,941 deaths, of which almost 75% were men. After a low incidence in childhood, adolescence and youth are risk stages where the number of cases multiplies by 20, with about 300 suicides in the 15 to 29 age group. Afterwards, cases steadily increase with age, reaching a peak between 45 and 64 years. Thus, suicide is a major issue that can occur at different life stages. What are the causes and risk factors behind suicide? What significance do associated pathologies, such as depression, have for this phenomenon? How is the prevention of suicidal behaviours, early detection, or care for people at risk and their families approached?